Events relating to medicine

Medicine men in Peru practise trephination, cuttting holes in the skulls of brave or foolhardy patients

Indian medical theory maintains that the body consists of three humours - spirit, phlegm and bile

The Alexandrian school of medicine develops an alarming form of clinical anatomy – human vivisection

The Roman surgeon Cornelius Celsus describes in De Medicina how to cut stones from a patient's bladder

A new doctor, Galen, is appointed to look after the gladiators at Pergamum

Medieval Europe's first institute of higher education is established, with the founding of the medical school at Salerno

The first illustrated manual of surgery is written by Abul Kasim, an Arab physician in Cordoba

The Persian scholar Avicenna, author of encyclopedic works on philosophy and medicine, spends the last part of his life in Isfahan

Conjoined twins Mary and Eliza Chulkhurst are born in Biddenden, in Kent

Leonardo da Vinci begins an unprecedented series of detailed anatomical drawings, based on corpses dissected in Rome

Eucharius Rösslin publishes the first textbook for midwives, later translated into English as The byrthe of mankynde

Ambroise Paré, the greatest surgeon of his day, publishes an account of how to treat gunshot wounds

Samuel Pepys has a two-ounce stone cut from his bladder, in an operation carried out at home in the presence of his family

The first successful human blood transfusion is achieved in Paris by Jean Baptiste Denis, apparently saving the life of a 15-year-old boy

Lady Mary Wortley Montagu, observing the Turkish practice of inoculation against smallpox, submits her infant son to the treatment

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